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Ronald Keith Siegel (b. 1943) is an American psychiatrist, research professor in the Department of Psychiatry and Biobehavioral Sciences at the University of California, Los Angeles (as recently as 2005), and the author of several noted studies and books on psychopharmacology, hallucination, and paranoia. Siegel has studied, lectured, and conducted research at Brandeis University, Harvard Medical School, Dalhousie University, and the Albert Einstein College of Medicine, and has been a consultant to several government commissions on drug use. His research has focused on the effects of drugs on human behavior, and has included numerous clinical studies in which human volunteers (sometimes referred to by Siegel as "psychonauts") have taken drugs such as ketamine, LSD, marijuana, mescaline, psilocybin, and THC.

In 2005, Siegel was an expert witness for the defense in the Robert Blake murder trial, testifying on the long-term effects of methamphetamine and cocaine use. According to the jury foreman in the trial, Siegel was "one of the most compelling witnesses" in discrediting the testimony of Ronald Hambleton, who claimed that Blake had asked him to murder Bonnie Lee Bakley. CNN.com - Actor Robert Blake acquitted of his wife's murder - Mar 17, 2005 In the course of his testimony in the Blake trial, Siegel disclosed that in one study, he had taught monkeys to smoke crack cocaine. The New York Times > National > Actor's Trial, Complete With Pulp Novel Characters, Draws to a Close

In the early 1980s, Siegel administered large oral doses of LSD to two elephants.

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