A longtime artist for many comic publishing companies including Marvel, DC, and Image, Mike Miller is most known for his work on the comic book adaptation of George R. R. Martin's Hedge Knight series, Robert Jordan’s New Spring as well as his work on DC’s JLA and Adventures of Superman.

Miller created and wrote The Imaginaries, which was published by Image Comics before starting his own publishing company, Alias Enterprises, to publish the series, among others. The series is returning through Darren Davis's Bluewater Productions.

In 2008, the option to his comic book series 'Deal with the Devil' was sold to Lionsgate Films , although no work on the project has been announced.

Miller currently draws a pair of established webcomics on his site Comicstripclub: Electronic Tigers, a slice-of-life gaming webcomic, and RLC (Right Left Center), a political cartoon series with a conservative viewpoint.