After attending Columbia College Chicago, Meno spent time working as a flower delivery truck driver and art therapy teacher at a juvenile detention center. His first novel Tender as Hellfire was published when he was only 24 and received strong reviews from sources like Library Journal. His short fiction has appeared in literary magazines like Tri-Quarterly, Ninth Letter, A hub for short fiction, and Other Voices. Meno's work is known for the use of natural language and realistic dialogue, as well as frequent forays into absurdity. He currently teaches fiction writing at Columbia College Chicago. He is a frequent contributor to Punk Planet magazine, where his comic strip Iceberg Town is featured.