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Gonorrhoea and Its Complications in the Male and Female
Gonorrhoea and Its Complications in the Male and Female Author:David Watson General Books publication date: 2009 Original publication date: 1916 Original Publisher: Kimpton Notes: This is a black and white OCR reprint of the original. It has no illustrations and there may be typos or missing text. When you buy the General Books edition of this book you get free trial access to Million-Books.com where you can select ... more »from more than a million books for free. Excerpt: CHAPTER II BACTERIOLOGY OF GONORRHOEA The first successful attempt to find the causative organism of gonorrhoea was that of Neisser. While assistant in the Breslau Skin Clinic in 1879, he published an article entitled " On a Characteristic Micrococcus of Gonorrhoea," in which he described the microscopic appearance of the gonococcus as seen in urethral and conjunctival pus. Neisser's discovery was rendered possible by the previous work of Weigert and Koch, who had introduced the process of bacteria staining. His observations were confirmed by others, but all attempts to grow the organism on artificial media failed until Bumm, in 1885, successfully used solidified serum derived from the human placenta. The separation of the gonococcus in pure culture enabled experimental inoculations to be undertaken on the human subject, and the successful issue of these operations conclusively demonstrated the causal relationship of the gonococcus to the disease. Wertheim simplified the process of culture by introducing a serum agar medium, and blood agar or serum agar is now in common use as a culture medium. Microscopic appearance of the gonococcus. -- The gonococcus belongs to the diplococci group. In outline it is plano-convex or bean-shaped, and the pairs lie with their concave or plane surfaces opposing, as shown in Plate II, leaving usually a distinct spacebetween the cocci. They can be recognised in unstained films, and are well seen by dark field illumination. They have no capsule, have no power of movement and do not form spores. There is considerable variation in size, but the...« less