On the eve of Mary Sue Prescott's 45 birthday, she is joined by her 3 closest friends, Gretchen, Pamela,and Dixie, at the lakeside cabin that has been their refuge for years. This meeting is not strictly a celebration, since Mary Sue is scheduled to undergo a mastectomy the following morning. At the same time they're dealing with Mary Sue's operation, another crisis arises. The 3 women must make a decision that results in a haunting and terrifying secret.