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Emerging Technologies in Transfusion Medicine
Emerging Technologies in Transfusion Medicine Author:Christopher P. Stowell, MD, PhD, Walter H. Dzik Transfusion medicine is rapidly changing from what was a relatively narrowly focused field with a limited diagnostic and therapeutic scope to one that embraces fundamental elements of immunology, stem cell biology, the inflammatory response and hemostatis. This shift in focus is in response to the accelerated pace of advances in biomedical resea... more »rch. No longer constrained to diagnoses based on blood group serology or to therapies based on a limited number of blood components and derivatives, transfusion medicine is redefining itself through the clinical application of modern biotechniques.
In Emerging Technologies in Transfusion Medicine examples of the emerging technologies that are transforming both diagnostic and therapeutic aspects of the field are highlighted, offering a deeper understanding and an informed evaluation necessary for their application.
Highlights:
New approaches to screening donor blood for prions and bacteria
Use of phage display technology to develop new diagnostic tools or therapeutic agents
Use of a variety of molecular biological techniques
Potential application of gene array technology and proteomics
New therapeutic agents in transfusion medicine
Agents for intervening in a pathogenic process that is fundamental to transfusion medicine
Use of dendritic cells as immunotherapy agents
Advances in pathogen inactivation technology
Review of first-generation oxygen therapeutics and how this experience is influencing the next generation of candidate blood substitutes« less