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Aging Skin: Current and Future Therapeutic Strategies
Aging Skin Current and Future Therapeutic Strategies Author:Linda D. Rhein, PhD, and Joachim W. Fluhr, MD Aging Skin presents leading-edge strategies to treat problems of aging skin. Current concepts are presented, along with fundamental research detailing the biochemical mechanisms underlying photodamage-the hallmark of aging skin. Based on the premise that aging and senescence occur due to a deterioration of cutaneous repair systems, topics covere... more »d include:
-Novel approaches using growth factors that regulate fibrosis to facilitate cutaneous wound repair while preventing solar scar
-Role of matrix metalloproteinases in the repair of photodamage
-Role of angiogenesis and lymphangiogenesis in response to photodamage and strategies to regulate these processes
-DNA repair and oxidative stress-resistant systems that aid in combating aging skin
-Hormonal influences on skin aging, benefit of hormone replacement therapy and role of nutrition
-Nonenzymatic glycation of matrix proteins due to oxidative stress-altering functionality and strategies to block such untoward reactions
-Success of current treatments retinoic acid, dermabrasion, Botox, peels and fillers
-Design of the optimal sunscreen for prevention of photodamage
-New skin-whitening strategies to reduce age spots by influencing melanogenesis« less