Divalproex Manic Depression A Guide Author:James W. Jefferson, John H. Greist Manic depression (bipolar disorder) is a mental and emotional condition characterized by wide and often disabling mood swings. It is estimated that at least 13 out of every 1,000 people will have some form of manic-depressive illness in their lifetimes. Divalproex, a drug commonly prescribed for specific forms of epilepsy, has become a ... more » well-established treatment for acute mania. In this booklet, Drs. Jefferson and Greist describe the benefits and limitations of using divalproex. (Previously published as Valproate and Manic Depression: A Guide.)« less